Dr Charis Costopoulos

Dr Costopoulos performs a range of treatments, including:

• Echocardiography
• Coronary angiography
• Coronary angioplasty (stenting)
• Transcatheter Aortic Valve Implantation (TAVI)
• Transcatheter mitral and tricuspid edge-edge-repair (e.g. MitraClip, TriClip, PASCAL)
• Patent Foramen Ovale (PFO) closure
• Cardiac coronary CT scanning
• Optical coherence tomography
• 24 tape monitoring
• 24 hour blood pressure monitor
• Exercise tolerance testing
• CardioPulmonary exercise testing
• Tilt table testing
• Interventional cardiology
• Cardiovascular risk assessment

Some of the conditions he commonly treats are:

• Angina (chest pain)
• Coronary artery disease
• Hypertension (high blood pressure)
• High cholesterol
• Valve disease
• Palpitations and fainting
• Those at high-risk of heart disease

Memberships:

• General Medical Council 
• Royal College of Physician 
• British Heart Valve Society 
• European Society of Cardiology

Clinical Posts:

• Current NHS practice - Royal Papworth 
• Clinical Lead for Non-Coronary Intervention

Dr Charis Costopoulos has a keen interest in clinical research - his articles are regularly published in the medical literature as well as presentations at national and international meetings.

Key Publications

• Costopoulos C, Gu S, Ahmad M, Huang Y, Hakim D, Maynard C, Cefalo N. Combined Low Endothelial Shear Stress and High Plaque Structural Stress Heterogeneity Predicts Non-Culprit Major Adverse Cardiovascular Events; Insights From the PROSPECT Study. AHA 2022. DOI:10.1161/circ.146.suppl_1.10038
• Costopoulos C, Gu S, Hakim D, Umit Coskun A, Cefalo N, Huang Y, Stone W G, Stone H P, Bennett R M. The Location of Combined High-Risk Low Endothelial Shear Stress and High Plaque Structural Stress is Distant from the Minimal Lumen Area in the Majority of Coronary Plaques Responsible for Major Adverse Cardiac Events. AHA 2022. DOI:10.1161/circ.146.suppl_1.13156
• Gu S, Costopoulos C, Huang Y, Bourantas V C, Woolf A, Sun C, Teng Z, Losdat S, Raber L, Samady H, Bennett R M. High-intensity Statin Treatment Is Associated with Reduced Plaque Structural Stress and Remodelling of Artery Geometry and Plaque Architecture. Nov 2021. DOI:10.1093/ehjopen/oeab039. License CC BY 4.0
• Gu S, Costopoulos C, Huang Y, Bourantas V C, Woolf A, Sun C, Teng Z, Raber L, Samady H, Bennett M. STATINS REDUCE PLAQUE STRUCTURAL STRESS THROUGH REMODELING ARTERY GEOMETRY AND PLAQUE ARCHITECTURE. Journal of the American College of Cardiology 2021, DOI:10.1016/S0735-1097(21)01365-6
• Costopoulos C, Maehara A, Huang Y, Brown J A, Gillard H J, Teng Z,  Stone W G, Bennett R M. Heterogeneity of Plaque Structural Stress Is Increased in Plaques Leading to MACE. 
• JACC. Cardiovascular imaging 2019. DOI:10.1016/j.jcmg.2019.05.024, License CC BY 4.0
• Costopoulos C, Timmins L, Huang Y, Hung O, Molony D, Brown J A, Davis E, Teng Z, Gillard H J, Samady  H, Bennett R M. Impact of combined plaque structural stress and wall shear stress on coronary plaque progression, regression, and changes in composition. European Heart Journal 2019. DOI:10.1093/eurheartj/ehz132, License CC BY 4.0