What medications are used for IBD?
Anti-inflammatory medications are often the first step in the treatment of IBD. These medications include corticosteroids, such as prednisone and budesonide. They can help to reduce inflammation in the body, but they don’t work for everyone with ulcerative colitis or Crohn’s disease.
What are the differences between Crohn’s disease and ulcerative colitis?
One of the main differences between these two gastrointestinal conditions is the part of the digestive tract that they affect. Ulcerative colitis occurs in the colon and rectum (large bowel), while Crohn’s disease can occur anywhere in the digestive tract. So, for people with ulcerative colitis, abdominal pain is often limited to the left side of the abdomen, while people with Crohn’s disease may have abdominal pain anywhere in the abdomen. Since Crohn’s disease affects more of the GI tract, it can cause different symptoms that are not seen with ulcerative colitis. These may including mouth ulcers (canker sores) that develop around the base of the gums and anal fistulas (anal fissures) which are splits or tears at the end of the anal canal.
What are the main triggers for IBD?
While the exact cause of IBD is unknown, the triggers involve a combination of genetic susceptibility, environmental factors, and immune system dysregulation. Things like smoking, certain medications like anti-inflammatories and antibiotics, and stress are known environmental triggers. Diet and infections can also play a role in flare-ups. Overall, IBD develops when these external factors interact with genetic risk, leading to abnormal immune responses in the gut.
What happens if IBD is left untreated?
If IBD, including Crohn's disease and ulcerative colitis, is left untreated, you can experience a range of serious complications affecting all areas of the body, (e.g abscess, narrowing of the bowel), some of which can be life-threatening such as perforation and over a long time increase your chance of developing cancer. If you have symptoms or a diagnosis of IBD, it’s important to seek specialist care so you can receive effective ongoing treatment and monitoring.