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A liver function test can be carried out with a blood test. This will assess and measure the health and function of your liver by looking at specific markers. A liver function test can also be used to monitor a condition affecting your liver and determine how well it is responding to treatment.
What does a liver function test check for?
A blood test is used to check your liver function by analysing a number of different proteins. This includes:
Alanine transaminase (ALT) – a liver enzyme that converts proteins into energy for your liver cells. If you have liver damage, your ALT levels can be elevated.
Aspartate transaminase (AST) – an enzyme that breaks down amino acids in the body. High levels may indicate liver damage or disease.
Alkaline phosphatase (ALP) – an enzyme in your liver and bones which breaks down proteins. High levels of ALP can mean you have damage or disease of your liver.
Albumin and total protein – albumin is a protein made by your liver. Low levels of albumin and total protein may mean you have liver damage or disease.
Bilirubin – a substance produced when red blood cells are broken down. It passes through the liver and is removed from the body in your stool. High levels of bilirubin may indicate liver damage or disease.
Gamma-glutamyltransferase (GGT) – an enzyme in your blood that, if elevated, can mean you have liver or bile duct damage.
L-lactate dehydrogenase (LD) – if found in high quantities, this enzyme can indicate potential liver damage.
Prothrombin time (PT) – your prothrombin time refers to the time it takes for your blood to clot. The higher your PT is, the higher your risk of liver damage.
It is important to note that abnormal results of a liver function test do not always indicate liver disease. At OneWelbeck, our consultants will always discuss and explain your results to help you fully understand what they mean.