Dr James Alexander

Consultant Gastroenterologist and Honorary Senior Lecturer

Digestive Health

Sub-speciality: Gastroenterology.

Overview

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Overview

Dr James Alexander is a Consultant Gastroenterologist at One Welbeck, St Mark’s Hospital and Imperial College Healthcare Trust, London and an Honorary Senior Clinical Lecturer in the Department of Metabolism, Digestion and Reproduction at Imperial College London.

About Dr James Alexander

Dr Alexander completed his undergraduate medical training at the University of Cambridge and Imperial College. He was awarded his PhD for research on the role of the gut microbiome in colorectal cancer and he went on to be a NIHR academic clinical lecturer in gastroenterology at Imperial College London. He completed his specialist training in gastroenterology in the North West London region.
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He performs upper and lower GI endoscopy, and conducts general gastroenterology and specialist IBD clinics including complex and joint medical/surgical IBD clinics.
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Dr Alexander's research interests include exploring the role of the gut microbiota in determining colorectal cancer and IBD pathogenesis, complications and treatment responses, as well as studying the impact of IBD therapies on immune responses to vaccination. He was the lead author on the British Society of Gastroenterology (BSG) position statement on COVID-19 vaccination for patients with IBD.
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He is a member of the BSG IBD Clinical Research Group and the BSG Gut Microbiota for Health expert panel. In 2023 he was awarded the British Society of Gastroenterology Young Gastroenterologist of the Year in Clinical and Translational Science.

Areas of Expertise

Dr Alexander is an expert in the following conditions: 

He also is an expert in Upper and Lower GI Endoscopy (OGD and Colonoscopy)

Additional Information

Additionally, Dr Alexander also practices at the following establishments: 

  • Consultant Gastroenterologist, Imperial College Healthcare Trust and St Mark's Hospital, London
  • Honorary Senior Lecturer, Imperial College London

Active memberships:

  • Member of the Royal College of Physicians (MRCP)
  • British Society of Gastroenterology
  • European Crohn's and Colitis Organisation (ECCO)

Professional Awards:

  • British Society of Gastroenterology Young Gastroenterologist of the Year (Clinical & Translational Science) 2023

Research Highlights

Dr Alexanders notable publications: 

Gut microbiota modulation of chemotherapy efficacy and toxicity
JL Alexander, ID Wilson, J Teare, JR Marchesi, JK Nicholson, JM Kinross
Nature reviews Gastroenterology & hepatology. 2017: 14 (6), 356-365
https://www.nature.com/articles/nrgastro.2017.20
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International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis
AJ Scott, JL Alexander, CA Merrifield et al.
Gut. 2019: 68 (9), 1624-1632
https://gut.bmj.com/content/68/9/1624
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COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study
JL Alexander, NA Kennedy, H Ibraheim et al.
The lancet Gastroenterology & hepatology. 2022: 7 (4), 342-352
https://www.thelancet.com/journals/langas/article/PIIS2468-1253(22)00005-X/fulltext
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SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group …
JL Alexander, GW Moran, DR Gaya et al.
The Lancet Gastroenterology & Hepatology 2021: 6 (3), 218-224
https://www.thelancet.com/journals/langas/article/PIIS2468-1253(21)00024-8/fulltext
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Pathobionts in the tumour microbiota predict survival following resection for colorectal cancer
JL Alexander, JM Posma, A Scott et al.
Microbiome. 2023: 11 (1), 100
https://link.springer.com/article/10.1186/s40168-023-01518-w

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Dr James Alexander is a Consultant Gastroenterologist at One Welbeck, St Mark’s Hospital and Imperial College Healthcare Trust, London and an Honorary Senior Clinical Lecturer in the Department of Metabolism, Digestion and Reproduction at Imperial College London.