Dr Aran Singanayagam
Consultant Respiratory Physician
Lung Health

Overview
Dr Aran Singanayagam is a Consultant Respiratory Physician at OneWelbeck and Royal Brompton and Harefield Hospitals. He is a recognised international expert in airways diseases (asthma, COPD, bronchiectasis), respiratory infections (acute and chronic) and long COVID. Dr Singanayagam also leads an active research program, spearheading patient-focussed research studies and clinical trials.
About Dr Aran Singanayagam
Dr Aran Singanayagam is a fully qualified Consultant Physician with GMC Registration 6120429. He completed his medical qualification at the University of Edinburgh in 2005 achieving distinction in his final examinations alongside a first class intercalated BSc in Physiology. His specialist respiratory medicine training occurred primarily at St Mary’s, Royal Brompton and Harefield hospitals.
Dr Singanayagam currently sees both NHS and private patients. He specialises in all aspects of respiratory medicine (any condition or symptom affecting the lungs/breathing). This includes asthma, COPD/emphysema, lung infections (acute and chronic), post COVID19 respiratory problems, bronchiectasis, sleep disorders, pneumonia, tuberculosis and allergic lung disease. As a recognised international expert, Dr Singanayagam is frequently asked to provide second opinions for difficult cases.
In addition to clinical responsibilities, Dr Singanayagam also leads a translational research group which studies the lung's immune system with the aim of developing new therapies for respiratory diseases. He spearheads a range of patient-focussed studies and clinical trials. He has been awarded >£4million in research funding including a recent ~£1.9million grant by the Medical Research Council to study the role played by viruses in promoting flare-ups of the lung condition bronchiectasis. Dr Singanayagam has received prestigious investigator awards from the British Thoracic Society (BTS), the European Respiratory Society (ERS) and the Worshipful Society of Apothecaries. He is a member of the BTS Science and Research Committee. He sits on the Editorial Board of The European Respiratory Journal and the American Journal of Respiratory and Critical Care Medicine and has published over 100 papers to date with a H index of 52.
Dr Singanayagam is internationally recognised as a leading respiratory clinical academic and regularly gives lectures at scientific conferences and provides commentary in the scientific and mainstream media. More information about Dr Singanayagam's research group is available at the laboratory website: https://www.singanayagamlab.com/.
Areas of Expertise
Dr Aran Singanayagam commonly treats:
- Respiratory infections (acute and chronic)
- Airways diseases (asthma, chronic obstructive pulmonary disease/emphysema, bronchiectasis)
- Long COVID
- Unexplained respiratory symptoms - chronic cough, breathlessness, chest pain
- Sleep disorders
He performs a range of treatments including:
Additional Information
Dr Aran Singanayagam's active memberships:
- Member of British Thoracic Society Science and Research Committee
- Editorial Board Member, American Journal of Respiratory and Critical Care Medicine
- Editorial Board Member, European Respiratory Journal
Dr Aran Singanayagam currently holds clinical posts at:
- Royal Brompton and Harefield Hospitals, London (NHS)
- 77 Wimpole Street, London (private)
Dr Aran Singanayagam's professional awards include:
- ACS Infectious Diseases Early Career Prize (2025)
- British Thoracic Society Mid-Career Investigator Prize (2024)
- Top peer reviewer Award, American J Respiratory and Critical Care Med (2022)
- Top Peer Reviewer Award, European Respiratory Journal (2020)
- Apothecaries prize for best research paper on therapeutics theme (2019)
- Rising Star award, International Workshop for Lung Health, Monaco (2016)
- British Thoracic Society Early Career Investigator Prize (2015)
- COPD research award – European Respiratory Society (2012).
Research Highlights
Dr Aran Singanayagam's notable publications include:
- Singanayagam A et al. Neutrophil extracellular traps drive immunopathogenesis of virus-induced COPD exacerbations. Nature Communications 2024;15: 5766. https://www.nature.com/articles/s41467-024-50197-0
- Singanayagam A et al. A persistent neutrophil-associated immune signature characterises post-COVID19 pulmonary sequelae. Science Translational Medicine. 14(671):eabo5795.
https://www.science.org/doi/full/10.1126/scitranslmed.abo5795?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org - Singanayagam A et al. Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial. Thorax. 2022 Oct;77(10):950-959. https://thorax.bmj.com/content/77/10/950.long
- Singanayagam A et al. Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease. J Clin Invest 2022. 132(8):e120901. https://www.jci.org/articles/view/120901
- Singanayagam A et al. Virus-induced Volatile Organic Compounds Are Detectable in Exhaled Breath during Pulmonary Infection. Am J Respir Crit Care Med 2021;204(9):1075-1085. https://www.atsjournals.org/doi/10.1164/rccm.202103-0660OC?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
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