Dr Justin Garner

Sub-specialties: COPD, Lung Cancer, Lung Nodules, Interventional Bronchoscopy, Respiratory Medicine, Lung Health.

02036532006

Overview

Dr Garner is a Consultant Respiratory Physician with sub-specialty expertise in COPD, lung cancer, and pulmonary nodule evaluation and treatment. He is an active researcher of small airways disease, inflammatory biomarkers, and medical device innovation.

About Dr Justin Garner

Dr Garner is a Respiratory Physician here at OneWelbeck Lung Health. He qualified from Imperial College School of Medicine, UK, in 2008. He trained as a respiratory specialist in the North West Thames deanery and completed his PhD in Interventional Bronchoscopy under Professors Pallav Shah and Dr Omar Usmani in 2020. During this time, he evaluated several therapies including endobronchial valves for patients with COPD.

He has worked as a consultant respiratory physician at the Royal Brompton Hospital since October 2021. Dr Justin Garner's research interests include small airways disease, inflammatory biomarkers, and medical device innovation. He has been recognised with the Royal College of Physicians / National Institute Clinical Research Network award for Outstanding Leadership in Research in 2017 (https://www.rbht.nhs.uk/researchers-recognised-outstanding-leadership) and the European Respiratory Society Interventional Pulmonology grant in 2019.

Dr Justin Garner has published multiple articles and book chapters on various respiratory topics including novel treatments for patients with COPD, notably endobronchial valve therapy.

Areas of Expertise

Dr Justin Garner has specialist expertise in the following:

Management of lung cancer and pulmonary nodules
Lung volume reduction (e.g., endobronchial valves)
Novel bronchoscopic therapies for chronic obstructive pulmonary disease (COPD)
Management of general respiratory conditions.

Additional Information

Clinical Posts:

Consultant Respiratory Physician, Royal Brompton Hospital
Honorary Senior Clinical Lecturer, Imperial College London

Memberships:

British Thoracic Society
European Respiratory Society
Fellow of the Royal College of Physicians

Practise locations:

Royal Brompton Hospital - Wimpole Street
Royal Brompton Hospital - Fire Station
One Welbeck

Awards:

FRCP
PhD
European Respiratory Society Interventional Pulmonology grant in 2019
Royal College of Physicians / National Institute Clinical Research Network award for Outstanding Leadership in Research in 2017 (https://www.rbht.nhs.uk/researchers-recognised-outstanding-leadership).

Qualifications:

Aug 2006 - BSc in Medical Sciences (Endocrinology): Upper 2nd Class Honours
Aug 2008 - MBBS (Imperial College London)
July 2011 - MRCP (London)
Jan 2021 - CCT in General Internal Medicine and Respiratory Medicine
Feb 2021 - PhD (Imperial College London): ‘Impact of surgical and of bronchoscopic lung volume reductions in patients with severe emphysema and hyperinflation on lung structure, function and inflammation’.
Jan 2023 - FRCP (London)

Research Highlights

1. Garner J, Kemp SV, Toma TP, Hansell DM, Polkey M, Shah PL, Hopkinson NS. Survival after Endobronchial Valve Placement for Emphysema: A 10-Year Follow-up Study. Am J Respir Crit Care Med. 2016 Aug. 194(4).

2. Kemp SV, Slebos DJ, Kirk A, Kornaszewska M, Carron K, Ek L, Broman G, Hillerdal G, Mal H, Pison C, Briault A, Downer N, Darwiche K, Rao J, Hubner RH, Ruwwe-Glosenkamp C, Trosini-Desert V, Eberhardt R, Herth FJ, Derom E, Malfait T, Shah PL, Garner JL et al. A Multicenter Randomized Controlled Trial of Zephyr Endobronchial Valve Treatment in Heterogeneous Emphysema (TRANSFORM). Am J Respir Crit Care Med. 2017 Dec 15;196(12):1535-1543.

3. D’Hooghe JNS, Goorsenberg AWM, Ten Hacken HT, Weersink EJM, Roelofs JJ, Mauad T, Shah PL, Annema JT, Bonta PI, TASMA research group (Garner J). Airway smooth muscle reduction after bronchial thermoplasty in severe asthma correlates with FEV1. Clin Exp Allergy. 2019 Apr;49(4):541-544.

4. Garner JL, Garner SD, Hardie RJ et al. Evaluation of a re-useable bronchoscopy biosimulator with ventilated lungs. ERJ Open Res. 2019 Apr 15;5(2):00035-2019.

5. Dransfield M, Bhatt S, Slebos DJ, Klooster K, Sciurba F, Shah P, Garner J et al. Impact of endobronchial valves on patient reported outcomes in severe emphysema. ERJ. 2019. 54:RCT447.

6. Slebos, Dj, Cicenia J, Sciurba FC, Criner GJ, Hartman JE, Garner J et al. Predictors of Response to Endobronchial Coil Therapy in Patients with Advanced Emphysema. Chest. 2019 May;155(5):928-937.

7. Valipour A, Shah PL, Pison C, Ninane V, Janssens W, Perez T, Kessler R, Deslee G, Garner J. Safety and Dose Study of Targeted Lung Denervation in Moderate/Severe COPD Patients. Respiration. 2019;98(4):329-339.

8. Shen M, Tenda ED, McNulty W, Garner J et al. Quantitative Evaluation of Lobar Pulmonary Function of Emphysema Patients with Endobronchial Coils. Respiration. 2019;98:70-81.

9. Garner JL, Kemp SV, Srikanthan K et al. 5-Year Survival after Endobronchial Coil Implantation: Secondary Analysis of the First Randomised Controlled Trial, RESET. Respiration 2020;99:154-162.

10. Dransfield MT*, Garner JL*, Bhatt SP et al. Effect of Zephyr Endobronchial Valves on Dyspnea, Activity Levels, and Quality of Life at One Year. Results from a Randomized Clinical Trial. Ann Am Thorac Soc. 2020 Jul;17(7):829-838. *joint first author.

11. Pison Christophe, Shah PL, Slebos DJ, Ninane V, Janssens W, Perez T, Kessler R, Deslee G, Garner JL et al. Safety of Denervation Following Targeted Lung Denervation (TLD) therapy for COPD: AIRFLOW-1 Three Year Outcomes. Am J Respir Crit Care Med. 2020;201:A1119.

12. Khalil K, Agbontaen K, McNally D, Love A, Mandalia S, Banya W, Starren E, Dhunnookchand R, Farne H, Morton R, Davies G, Orhan O, Lai D, Nelson M, Shah PL, Garner JL. Clinical characteristics and 28-day mortality of medical patients admitted with COVID-19 to a central London teaching hospital. J Infect. 2020 Sep;81(3):e85-e89.

13. Garner JL, Shaipanich T, Hartman JE, Orton CM, Caneja C, Klooster K, Thornton J, Sin DD, Slebos DJ, Shah PL. A prospective safety and feasibility study of metered cryospray for patients with chronic bronchitis in COPD. ERJ. 2020 Dec 17;56(6):2000556.

14. Hartman JE, Shah PL, Sciurba F, Herth FJ, SLebos DJ, RENEW study group (Garner JL). Endobronchial coils for emphysema: Dual mechanisms of action on lobar residual volume reduction. Respirology. 2020 Nov;25(11):1160-1166.

15. Soni S*, Garner JL*, O’Dea KP, Koh M, Finney L, Tirlapur N, Srikanthan K, Tenda ED, Aboelhassan AM, Singh S, Wilson MR, Wedzicha JA, Kemp SV, Usmani O, Shah PL, Takata M. Am J Physiol Lung Cell Mol Physiol. 2021 Jan 1;320(1):L73-L83. *joint first author.

16. Garner JL, Biddiscombe MF, Meah S, Lewis, A, Buttery SC, Hopkinson NS, Kemp SV, Usmani OS, Shah PL, Verbanck S. Endobronchial Valve Lung Volume Reduction and Small Airways Function. Am J Respir Crit Care Med. 2021 Feb 17.

17. Pison Christophe, Shah PL, Slebos DJ, Ninane V, Janssens W, Perez T, Kessler R, Deslee G, Garner JL, Hartman JE, Degano B, Mayr A, Mayse M, Peterson AD, Valipour A. Safety of denervation following targeted lung denervation therapy for COPD: AIRFLOW-1 3-year outcomes. Respir Res 22, 62 (2021).

18. Hartman JE, Klooster K, Augustijn SWS, van Geffen WH, Garner JL, Shah PL, Ten Hacken NHT, Slebos DJ. Identifying Responders and Exploring Mechanisms of Action of the Endobronchial Coil Treatment for Emphysema. Respiration 2021;100:443–451

19. Garner JL. Impact of surgical and of bronchoscopic lung volume reductions in patients with severe emphysema and hyperinflation on lung structure, function and inflammation. PhD Thesis. Imperial College London, Feb 2021.

20. Vijayakumar B, Boustani K, Ogger PP, Papadaki A, Tonkin J, Orton CM, Ghai P, Suveizdyte K, Hewitt RJ, Desai SR, Devaraj A, Snelgrove RJ, Molyneaux PL, Garner JL, Peters JE, Shah PL, Lloyd CM, Harker JA. Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways

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