Areas of Expertise

Tests he performs including:

• Colonoscopy
• Endoscopy
• High Resolution Manometry
• Impedance-pH monitoring
• Wireless pH monitoring
• Oesophageal physiology

Treatments he provides include:

• Behavioural modification therapy
• Botox of the oesophagus and stomach
• Dilatation of the oesophagus and stomach
• Endoscopic Mucosal Resection
• Irritable bowel syndrome (IBS)
• Per-oral Endoscopic Myotomy (POEM)
• Radio-frequency Ablation
• Small Intestinal Bacterial Overgrowth (SIBO)
• Trans-oral Incisionless Fundoplication (TIF),

Conditions he commonly investigates and treats include:

• Dysphagia (swallowing problems)
• Reflux, heartburn, regurgitation, LPR
• Chest pain
• Barrett’s oesophagus
• Achalasia
• Spasm and hypercontraction of the oesophagus
• Oesophageal diverticulum
• Eosinophilic oesophagitis
• Oesophageal stricture
• Rumination syndrome and Belching disorders
• Vomiting disorders
• Gastroparesis/Delayed gastric emptying
• Abdominal pain
• Bloating
• Irritable bowel Syndrome (IBS)
• Constipation
• Diarrhoea
• Anaemia
• Rectal bleeding
• Small intestinal bacterial overgrowth (SIBO)

About Dr Rami Sweis

Dr Rami Sweis is a Consultant Gastroenterologist at OneWelbeck. He has been working as a gastroenterology consultant for more than 10 years. Dr Rami Sweis is an upper and lower GI gastroenterologist and endoscopist. He treats problems from the throat and oesophagus, to the stomach and colon. He has a particular interest and expertise in upper GI benign disorders, including problems of function of the oesophagus and stomach, which have been the focus of much of his research and publications. He runs the Upper GI Physiology unit at both University College London Hospital and OneWelbeck, whereby he investigates problems of swallowing and reflux such as food sticking on swallowing, chest pain, heartburn, regurgitation and vomiting using tests such as High Resolution Manometry, Impedance-pH monitoring and Wireless pH monitoring. He also has a particular interest in conditions such as eosinophilic oesophagitis, Barrett’s oesophagus, achalasia as well as management of SIBO, diarrhoea, constipation and IBS.

Dr Rami Sweis always looks at patients holistically. He tries to offer support and help that is most suitable for the patient after taking into account all the problems, concerns and expectations. He listens carefully with an open mind and tries to minimise unnecessary tests and treatments wherever possible. All decisions are made with the patient, offering plenty of time to decide together what is most suitable together, whilst providing all information possible in the simplest, most understandable terms.

Dr Rami Sweis can offer a range of therapies, ranging from behavioural modification and targeted medicines, to endoscopic treatments such as using Botox, dilatation, POEM (per-oral endoscopic myotomy), TIF (trans-oral incisionless fundoplication), Zenker’s diverticulotomy, Radio-frequency ablation and others.

To listen to Dr Rami Sweis provide an overview of the common symptoms of reflux, and how it can be investigated in a healthcare setting, you can click the link here.

Research Highlights

Key Publications

• S Sanagapalli, A Plumb, R Sweis, Timed barium swallow: Esophageal stasis varies markedly across subtypes of esophagogastric junction obstruction. Neurogastroenterology and Motility. Jan 2022. DOI:10.1111/nmo.14322
• A Mari, R Sweis, Assessment and management of dysphagia and Achalasia. Clinical medicine 21(2):119-123. March 2021. DOI:10.7861/clinmed.2021-0069
• M R Fox, R Sweis, R Yadlapati, N Rommel, Chicago classification version 4.0© technical review: Update on standard high‐resolution manometry protocol for the assessment of esophageal motility. Neurogastroenterology and Motility. March 2021. DOI:10.1111/nmo.14120
• M Pesce, R Sweis, Advances and caveats in modern achalasia management. Therapeutic Advances in Chronic Disease. March 2021. DOI:10.1177/2040622321993437
• S Sanagapalli, R W Leong, K Patel, R Sweis, The Clinical Relevance of Manometric Esophagogastric Junction Outflow Obstruction Can Be Determined Using Rapid Drink Challenge and Solid Swallows. The American Journal of Gastroenterology. Oct 2020. DOI:10.14309/ajg.0000000000000988
• R Sweis, M Fox, High-Resolution Manometry—Observations After 15 Years of Personal Use—Has Advancement Reached a Plateau?. Current Gastroenterology Reports. Aug 2020. DOI:10.1007/s11894-020-00787-x
• S Sanagapalli, A Plumb, J Maynard, R W Leong, R Sweis, The timed barium swallow and its relationship to symptoms in achalasia: Analysis of surface area and emptying rate. Neurogastroenterology and Motility. June 2020. DOI:10.1111/nmo.13928
• S Ishaq, H Louis, S van-Meer, D Pohl, F Prat, D von-Renteln, R Sweis, J Tack, J Martinek, V L Zúñiga, E Savarino, R Tutuian, Endoscopic management of gastrointestinal motility disorders – Part 1: European Society of Gastrointestinal Endoscopy. Endoscopy. May 2020. DOI:10.1055/a-1160-5549
• B L A M Weusten, M Barret, A J Bredenoord, P Familiari, J M Gonzalez, J E van-Hooft, V L Zúñiga, H Louis, J Martinek, S van-Meer, H Neumann, D Pohl, F Prat, D von-Renteln, E Savarino, R Sweis, J Tack, R Tutuian, S Ishaq, Endoscopic management of gastrointestinal motility disorders – part 2: European Society of Gastrointestinal Endoscopy. Endoscopy. May 2020. DOI:10.1055/a-1171-3174
• R Sweis, M Fox, The global burden of gastro-oesophageal reflux disease: more than just heartburn and regurgitation. The Lancet Gastroenterology & Hepatology. March 2020. DOI:10.1016/S2468-1253(20)30002-9
• N J Trudgill, D Sifrim, R Sweis, M Fullard, K Basu, M McCord, M Booth J Hayman, G  Boeckxstaens, B T Johnson, N Ager, J de Caestecker, British Society of Gastroenterology guidelines for oesophageal manometry and oesophageal reflux monitoring. Gut. July 2019. DOI:10.1136/gutjnl-2018-318115
• S Sanagapalli, S Roman, A Hastier, R W Leong, K Patel, A Raeburn, M R Banks, R J Haidry, L B Lovat, D Graham, S Sami, R Sweis, Achalasia diagnosed despite normal integrated relaxation pressure responds favorably to therapy. Neurogastroenterology and Motility. Apr 2019. DOI:10.1111/nmo.13586
• Further publications from Dr Rami Sweis